I will say this. We dont work on them EVER for major failures, unless just a owners major neglect.
I have a 91 accord with 270K on it No major work. It is THE CHAMP.
If you are going with a CRV, some of the Mid to late 2000 models had a AC compressor problem (google it). The cases would just blow apart. About a 1300$ repair. The driveshaft U joints are not replaceable, as of the last I knew, and if one goes bad, the complete driveshaft is about a grand,but I have never seen one go bad yet.
Other than that, Ball joints, timing belt, waterpump and plugs every 100K plus routine fluid changes.
Brakes go about 30-40K depending on driving habbits.
I am all for supporting American Products, but the friggin Hondas are great vehicles. Almost any of them.