One problem I see is that you gain not only the cr250's powervalve, but also it's tranny gearing. This could be overcome probably with regearing, but it's something to think about. Plus like on any bike you would have to deal with the kicker going backwards, but with some sidecase work, this could probably be gotten around. Red rider put the powervavle on his bike, and has a nice write up about it on his webpage.
73 cr250m elsinore, 85 atc70, 85 250r flattracker, 87 250es bigred, 86 tecate, 2004 gas gas de300