I've dealt with this many times recently, i have probably rescued at least a dozen computers now with this crap on it. Boot into safe mode and if possible get a thumb drive and load it up on another computer and get TDSSKiller, Malwarebytes, and CCleaner. Run TDSS, clean anything it finds, run Malwarebytes and clean what it finds then reboot back into safe mode and full scan again, keep doing that until it doesnt find anything, then run CCleaner just to clear out temp files and clean up the registry. Once your all done you should be good to go, but also go disable system restore to delete all the restore points then re-enable. The reason being is you could have infected restore points as well.
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1984 Honda ATC200ES "Big Red"
1982 ATC200E "Hondie"
1988 TRX300FW "Project Quad" Still in progress....