Problems with changing from mineral oil to synthetic date back into the '70's when Mobil 1 first came out. It was an ester based oil and chemically attacked the standard gasket materials used back then. (cork & rubber, neoprene were the most common) The most common synthetic base used today is PAO (poly alpha olefin). It is completely compatible with any mineral oil. The more expensive oil will use POA with a little ester mixed in because the ester softens seals & gaskets. It also cleans better by breaking down carbon deposits.
The first fill with synthetics will usually get dark quickly because of the cleaning. This goes for any motor, not just trikes.
I run synthetics in everything I own, even my lawnmower.
One thing, break in a new motor with mineral oil, synthetics will keep the rings from seating.


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